Tissue Guarantee

About Cord Tissue

Umbilical cord tissue can be collected at the same time as your baby’s cord blood. His or her umbilical cord contains a special kind of stem cell called mesenchymal stem cells (MSCs), which are distinct from cord blood stem cells. Research suggests that in the future these cells could treat medical conditions that are untreatable today.

These special cells are being studied for their ability to regenerate bone, cartilage, tendons and neurons.

Currently, there are no medical treatments available using stem cells extracted from cord tissue; however, a significant amount of research is underway to better understand their value and importance to the scientific community.

Cryosite’s scientists have developed a method to extract and store these valuable cells for the potential uses they offer in the future.

No therapies are currently approved for cord tissue, and the future use of banked cord tissue will be dependent on regulatory approval of the processing and storage methods your bank has used.


Cryosite’s Tissue Viability Guarantee

Cryosite proves the viability of every cord tissue collected by extracting and expanding the valuable MSCs. We provide parents with peace of mind by providing photographic evidence to demonstrate that their baby’s expanded stem cells are viable prior to storage. Companies that simply freeze the umbilical cord cannot ensure that the cells banked are viable, which means you could be paying for nothing. If your baby’s tissue stem cells are not viable prior to storage we will let you know and refund your tissue fees.


Australia's Only Real Tissue Viability Guarantee

Don’t be misled by company’s who can’t prove they have the ability to store your child’s precious cord tissue in a viable state. 

Instead they only offer financial compensation in future years if your cells are dead when your child actually needs them.

You could be paying for nothing.

  • Only Cryosite tests and proves the viability of every child’s cord tissue when it is received in our laboratories.
  • Only Cryosite provide you with peace of mind, by providing photographic evidence that we have stored your baby’s tissue cells in a viable state.
  • Only Cryosite use validated patented methods that can back our unmatched “money back guarantee” that your child’s tissue stem cells are stored in a viable state - on day 1.  

Cord Tissue Banking – The Facts!

Cord tissue banking is in its infancy and cord tissue banks are not yet regulated by the TGA. When selecting a cord tissue bank it is essential that you ensure the quality of processing and storage methods used can effectively preserve your baby’s stem cells for future approved uses.

There are two different methods currently being provided within Australia:

  1. Freezing segments of umbilical cord.

  2. Isolation and freezing of the high value perivascular stem cells from the umbilical cord.

As each method has distinct advantages and disadvantages, and cord tissue storage is a very new and emerging area of stem cell science, we store all umbilical cord tissue using BOTH methods. This provides more options for potential treatments in the future.


Cord Tissue Storage Methods

There are two different methods currently being provided within Australia:

METHOD A - Freeze umbilical cord in segments (Available from all cord and tissue banks)
Advantages
  • All cell types are stored (Mesenchymal stem cells, endothelial & epithelial cells).
  • Known in the industry as the “minced tissue” or “slice and dice” method, it provides a quick and economical way to freeze cord tissue.

Disadvantages
  • This method does NOT isolate the valuable perivascular cells from the cord and significantly decreases their viability during storage.
  • The stem cells are NOT ready for expansion and treatment immediately when required.
  • The ability to isolate individual cell types from the minced frozen tissue is problematic, meaning they may not be able to be isolated for future expansion and use.
  • The validity of this method is the focus of growing international debate. The recent 2014 paper by Badowski^ published in Cytotherapy concluded that cord tissue processed by this method resulted in: "Poor cell recoveries and few viable cells” and concluded that, Poor cell yields and recoveries, along with slower growth characteristics, make (this) frozen CT a less-than-optimal choice for MSC banking" ^Cytotherapy (Volume 16, Issue 9, Pages 1313–1321, Sept 2014)
METHOD B - Isolate and freeze the perivascular stem cells (Specific to Cryosite)
Advantages
  • Isolation and storage of those stem cells found in the highly concentrated perivascular region of the umbilical cord. This the richest source of MSCs ever discovered^.
  • These MSCs are more biologically (physiologically) potent than adult stem cells. These MSCs differentiate into all tissues of the musculoskeletal system and also possess unique immuno-regulatory properties.
  • Isolating these stem cells before freezing optimises their long term storage viability.
  • The stem cells are ready for expansion and treatment immediately.

Disadvantages
  • This method is more expensive for cord tissue companies to perform.
  • The endothelial & epithelial cells are removed from the tissue before storage (not a problem if both methods are performed). ^Original research confirmed by Salgado et al., Baksh et al., Schugar et al. and Farias et al. (See our website for journal details)
Method A & B - Store Cord Tissue using both methods (Specific to Cryosite)
Advantages
  • Storage of cord tissue by both methods provides parents with more options for potential treatments in the future.
  • Cryosite do not offer storage of the entire cord only as we believe it has very low potential for future use. However, we store it just in case the stem cells found within this residual umbilical cord can ever be isolated and expanded using future technologies.